The Relationship Between Anemia, Fecal Stercobilinogen, Erythrocyte Survival, and Globin Synthesis in Heterozygotes for f3-Thalassemia
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چکیده
Erythrocyte survival, fecal stercobilinogen, chain ratios were so correlated. In the case and the a//3-chain synthesis ratio in reticuof bone marrow, on the other hand, the locytes and bone marrow (six cases only) ratio between a-chain and /3-chain synwere determined and related to the hemothesis was virtually 1, irrespective of the globin levels in ten heterozygous carriers degree of anemia. It is suggested that the of /3-thalassemia with different degrees of severity of anemia in heterozygous carriers anemia. Erythrocyte survival values were is independent of peripheral hemolysis low, though not related to the degree of and entirely attributable to destruction of anemia, whereas stercobilinogen values erythroblasts within the marrow. and changes in the peripheral blood a//3-
منابع مشابه
Balanced globin chain synthesis in hereditary persistence of fetal hemoglobin.
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